You may have ad / mal-ware. Further information can be found in the Troubleshoot Firefox issues caused by malware article.

Adblock Plus {web link} Blocks annoying video ads on YouTube, Facebook ads, banners and much more. Adblock Plus blocks all annoying ads, and supports websites by not blocking unobtrusive ads by default (configurable).

Adblock Plus Pop-up Addon {web link} Adblock Plus Pop-up Addon extends the blocking functionality of Adblock Plus to those annoying pop-up windows that open on mouse clicks and other user actions.

Forum; Adblock Plus Homepage {web link}

I'm getting this, and it's getting old really fast. Are you sure this isn't Firefox choosing to subject us to ads?

gorgill said

Audio ads pop up randomly, no new programs added prior to this starting. Kaspersky did not find any Virus such as Sekindo.

The problem was solved with the troubleshooting portion from Mozilla

That's good to hear. Can you tell us what solved the problem?

gorgill said

Audio ads pop up randomly, no new programs added prior to this starting. Kaspersky did not find any Virus such as Sekindo.

The program recommended by Mozilla Troubleshooting that fixed the problem was Malwarebytes Anti-Malware. I also added to add-ons to firefox Adblock Plus and Adblock Plus Pop-up Addon.

The program found 18 adware programs to remove.