Is this with many web pages, some, a few?

Start Firefox in Safe Mode {web Link} by holding down the <Shift>
(Mac=Options) key, and then starting Firefox. A small dialog should appear. Click Start In Safe Mode (not Refresh).

Is the problem still there?

The Menu does not contain the item " Restart with Add-ons Disabled...".

That is odd. Type about:support in the address bar and press enter. On the top-right should be a link to 'try Safe Mode.'

Wierd! I restarted safe and brought up Hotmail. The first few messages worked perfectly but then it was back to having to click to reset focus for each message.

How do I get Ad Blocker to work? I can't stand these flashing ads. It says it can be accessed from the tool bar. How?

Wierd! I restarted safe and brought up Hotmail. The first few messages worked perfectly but suddenly it was back to having to click to reset focus for each message.

How do I get Ad Blocker to work? I can't stand these flashing ads. It says it can be accessed from the tool bar.

Not the best idea to have two similar add-ons installed.

Ad-Aware Ad Block 1.2.1.028 
Adblock Plus 2.8.2

Try disabling Ad-Aware Ad Block and see if that helps.

I thought restarting in safe mode would eliminate both.

That fixed Ad Block. Where do I go with the focus problem?

Using Safe Mode disables all add-ons.

Your System Details shows;

Extensions;

Ad-Aware Ad Block 1.2.1.028 Adblock Plus 2.8.2
Having more than one program to do the same job may cause issues. Pick one and disable it. Restart Firefox.

After a test run, switch (restart FF) and see what works better for you.

So I've been running in safe mode and paging keys do not work unless I click for focus.

I called for more help.