https://support.mozilla.org/en-US/kb/how-to-fix-preferences-wont-save

Note: Some software, like Advanced SystemCare with Surfing Protection, can protect files in the Firefox profile folder against changes. If you have such software then check the settings or uninstall this software.

Refresh solved that problem, thanks, but now, the "options" window looks quite different than it did and I cannot find "cookie control"

In case you use "Clear history when Firefox closes" or otherwise clear history.

• do not clear the Site Preferences

• Options/Preferences -> Privacy & Security -> Firefox will: "Use custom settings for history": [X] "Clear history when Firefox closes" -> Settings
• https://support.mozilla.org/en-US/kb/delete-browsing-search-download-history-firefox

• clearing "Site Preferences" clears exceptions for cookies, images, pop-up windows, and software installation and exception for password and other website specific data
• clearing "Cookies" will remove all selected cookies including cookies with an "Allow" exception you may want to keep