I think that you would have to modify the permissions.sqlite file in each of the profiles and import or otherwise add the exceptions to this sqlite database.<br /> You could copy this file from a profile to you current computer and copy the modified file back. You can also consider to create an extension that you install globally that automatically imports this exception list once. For a new profile this can be achieved by placing a permissions.sqlite file in the \browser\defaults\profile\ folder. See also: *https://addons.mozilla.org/en-US/firefox/addon/exexceptions/ ----- *http://mike.kaply.com/2013/04/24/major-changes-coming-in-firefox-21/ *http://mike.kaply.com/2013/05/13/more-major-changes-coming-in-firefox-21/ *http://mike.kaply.com/2013/02/11/add-ons-in-the-distribution-directory/