"Ctrl + Shift + T" is the shortcut to reopen the last closed tab and "Ctrl + Shift + N" is the shortcut to reopen the last closed window, so those wouldn't be available for an extension. If you open a new window via "Ctrl + N" or "File -> New Window" then it open with the home page(s), so you can possibly set the home page to a blank page. You can possibly use a bookmark with the location set to "about:blank"and hold Shift and left-click this bookmark to open a blank window.

Hi, Thanks for the quick reply. I can already click the 'open new tab' icon while holding shift, which accomplishes your last suggestion without creating an about:blank bookmark. However, I was wondering if there is a way to create a keyboard shortcut to open a new window with one blank tab. Currently, using ctrl+n opens a new page with my five homepages, which I would like to keep. Sincerily, Tommy