I am sorry, but I really do not understand your question. Set up what? Thunderbird is a mail client. office365 is office productivity tools such as word processing. The two really do not interact at all.

Matt said

I am sorry, but I really do not understand your question. Set up what? Thunderbird is a mail client. office365 is office productivity tools such as word processing. The two really do not interact at all.

Sir,

We are using office365(specifically Outlook Web App) as our email. We always have to open IE/Google Chrome just to open mails. I want to use Thunderbird as Email Client but I don't know how to use it. As far as I know,there are setting to be change/set-up before I can use it(thunderbird).

Hope this clarify this. Thanks.

See https://support.office.com/en-gb/article/Settings-for-POP-and-IMAP-access-for-Office-365-for-business-or-Microsoft-Exchange-accounts-7fc677eb-2491-4cbc-8153-8e7113525f6c

if you don't qualify for IMAP or POP , then I suggest you fork out for this add-on https://addons.mozilla.org/en-US/thunderbird/addon/exquilla-exchange-web-services/ or use davmail http://davmail.sourceforge.net/index.html