If your add-ons are all deactivated after updating then there could be a problem with the extensions.json in the Firefox profile folder causing a new file getting created or even worse and you got a new profile folder.

What security software do you have in case that is the cause of this issue ?

I have compleptly uninstalled firefox and reinatlled, have been using just the Mircosoft Security and Paid Avast. Happens every time firefox updates on two diffrernt computers.

Your sites says "When you update Firefox, it automatically checks your add-ons and updates them to compatible versions when possible. If an add-on can't be updated and is no longer compatible, Firefox turns it off. This article shows you how to update those add-ons and get them working again."

Did that, have installed all updated to newest versions,

I want to turn this "OFF' if not I an going to use another browser, and recomend others that have a similar dislke of having to reactive thier addon, to switch.

Clearifiaction, used MS security , then swtiched to Avast, I use Avast on one of my computers that does a lot fo my Crypo stuff (mining,wallets, staking, ect), and MS security doesn't like anything to do with Crypto stuff.

This Firefox issues happens on two differnt computers, one decated to Crypto, and the other to 3D printing.